The Princess Margaret Hospital Foundation
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  • The first Princess Margaret Hospital Foundation lottery was in 1996.
  • Proceeds have been invested in innovative technology and in funding many of the world’s brightest scientists and doctors who work at the Ontario Cancer Institute (OCI), the research arm of Princess Margaret Hospital.
  • Over 1,000 researchers, trainees and staff are working at OCI to revolutionize cancer research, treatment and patient care.
Here are some of the innovative research programs that are having a real impact on patient treatment and care.

New Drug Discovery:
PMH has 80 clinical trials for new drugs in various stages of completion.
Promising new drug trials include:
  • A study led by Dr. Frances Shepherd with a new drug called Tarceva, indicates that it may increase survival rates in lung cancer patients while also improving negative side effects associated with standard treatments.
  • A major international study showed that the drug letrozole given after tamoxifen reduced by 44% the chance of breast cancer returning in post-menopausal women.
  • Another international study involving Dr. Warren Mason resulted in the development of a new standard of care for the treatment of glioblastoma, the most deadly form of brain cancer – heralding the first advance in treating this disease in 30 years.
Cancer Genomics:
Gene-based research is advancing our understanding of why some drugs work better for certain patients and will eventually allow us to customize drug treatments based on a person's genetic makeup.
Information Technology:
We are developing and implementing new information technology, which allows us to analyze multiple forms of patient data effectively and improves our ability to predict at a faster pace, what treatments will work best.
Image-Guided Therapy:
PMH has developed a world-leading program in imaging and radiation therapy that is allowing more precise and targeted radiation to be applied to tumors.
Applied Biophotonics:
PMH is conducting the first Canadian clinical trials using light therapy to target tumors and thus eliminate damage to healthy tissue. This new light activated photodynamic drug is called TOOKAD.
Cell Therapy:
We are entering a new era in innovative research and treatment options for leukemia patients - for example - we can now offer very specialized transplants using partially matched bone marrow donors. Previously, patients required a more complete match.
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The Campbell Family Cancer Research Institute
Ride to Conquer Cancer
PMH's Dr. Vera Peters first advocated the combination of radiation treatment and breast conserving surgery for women with early stage breast cancer.
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